Interval between insulin injection and breakfast in diabetes.
نویسندگان
چکیده
The relationship between the insulin-breakfast interval, postprandial increase in blood glucose, and glycaemic control was studied in 58 children with diabetes. Patients recorded insulin-breakfast intervals in a home diary over a seven day period, and during a 24 hour period at the weekend provided eight serial capillary dried blood spots for glucose analysis. The highest mean blood glucose value occurred two hours after breakfast and showed a significant correlation with fructosamine concentrations. Weekend insulin-breakfast intervals ranged from 2-30 minutes, with 70% reporting intervals of less than 15 minutes. There was a significant correlation between the weekend insulin-breakfast interval and the after breakfast increase in blood glucose with a mean increment of 0.4 mmol/l in the 30 minute group and 7.2 mmol/l in the 2 minute group. Over the whole study period, children with mean insulin-breakfast intervals of two to 12 minutes had a mean fructosamine concentration of 376 mumol/l compared with 341 mumol/l in those with intervals of 15-35 minutes. This study has shown that the interval between insulin injection and breakfast significantly influences the morning postprandial rise in blood glucose and consequently short term glycaemic control. It is therefore important that patients are encouraged to leave an interval of about 30 minutes between insulin injection and breakfast.
منابع مشابه
The effect of low glycemic index foods taken at dinner on blood glucose and insulin levels in patients with type 2 diabetes
Introduction: Diabetes is one of the most common endocrine diseases. With regard to the importance of blood glucose regulation in prevention of diabetic complications, glycemic and insulinemic response determination of foods containing carbohydrates is greatly important. The purpose of the present study, therefore, was to determine the effect of low glycemic index foods taken at dinner on fasti...
متن کاملInterval between insulin injection and eating in relation to blood glucose control in adult diabetics.
In a survey of 225 diabetics treated with insulin 24 (10.6%) claimed never to have received advice concerning the interval between insulin injection and eating. Of the remainder, 67 (33%) admitted disregarding advice and using shorter intervals. There was a significant (p less than 0.01) difference between the reported frequencies of clinical hypoglycaemia in patients using different intervals....
متن کاملTiming of pre-breakfast insulin injection and postprandial metabolic control in diabetic children.
A peak period of hyperglycaemia in insulin-dependent diabetics occurs after breakfast. A randomised crossover study was performed on nine diabetic children at home to study the effect of varying the time of their morning mixed injection of Monotard and Actrapid insulin on this hyperglycaemic peak. Performing the study at home minimised the children's stress.After diabetic control had been impro...
متن کاملA Randomized Clinical Trial Comparing Breakfast and Bedtime Administration of Insulin Glargine in Children and Adolescents with Type 1 Diabetes
BACKGROUND Insulin glargine provides effective glycemic control when administered at bedtime in adults. OBJECTIVE This study aims to investigate whether insulin glargine is equally effective if administered in the morning or at bedtime in combination with preprandial anologue insulin. METHODS Twenty-eight patients that have been treated with an intensified insulin regimen for at least one y...
متن کاملThe Effect of Interval Training On G6Pase Expression in Hepatic Tissue, Glucose and Insulin of Obese Rats with Type 2 Diabetic
Background: The objective of this experimental study was to determine the effect of 6 weeks of high intensity interval training (HIIT) on G6Pase expression in liver tissue, serum insulin and glucose and insulin resistance in obese rats with type 2 diabetic and compared with non-diabetic obese group. Methods: 28 male Wistar rats aged 10 weeks (220 ± 10 g) were obesed by 6 weeks of high-fat diet...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Archives of disease in childhood
دوره 71 3 شماره
صفحات -
تاریخ انتشار 1994